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News

Valproate and childbearing potential: new regulations

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Events

ABN/SBNS Joint meeting 19-21 September 2018 - registration now open. Abstract deadline extended to 25 June

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Jeremy Johnson

Hearing impairment in dementia: defining deficits and predicting impact

 Scope. Hearing impairment has been linked to clinical deterioration in dementia, with immense implications for public health and potentially opportunities for treatment. However, important questions remain: are hearing changes in dementia due primarily to deafness or altered brain processing of sounds? How does this relate to symptoms and daily life impact in different diseases? How does hearing impairment affect disease course and brain damage? My Fellowship aims to: i) assess and compare different aspects of hearing in patients with Alzheimer’s disease and primary progressive aphasia, a major dementia of middle life that profoundly affects processing of speech and other sounds; ii) establish how hearing changes relate to clinical symptoms, disability and care burden; iii) assess whether hearing impairment drives disease course, clinically and in the brain Methods. I will use a new, comprehensive test protocol to assess hearing and auditory brain functions systematically and over time in patients versus healthy older people. Associated brain changes will be assessed using MRI scanning. New hearing measures will be compared with standard hearing tests and measures of dementia diagnosis and impact. Outcomes and timeframe. Within the lifetime of my Fellowship, this work will generate new tools and markers that define and predict the clinical and brain impact of hearing impairment in major dementias, and how this affects the daily lives of patients and caregivers. Over the next five to ten years, my findings will inform future clinical trials and interventions for improving communication and auditory environments in people with dementia.

 

News

Valproate and childbearing potential: new regulations

Read More

Events

ABN/SBNS Joint meeting 19-21 September 2018 - registration now open. Abstract deadline extended to 25 June

Read More