Connections: ABN Virtual Meeting 2021
The live portion of the ABN Annual Meeting ‘Connections 2021’ took place in evening sessions on 29 April and the 6, 13 May, culminating in 2 full day meetings on 20 and 21 May. All sessions were recorded and will remain accessible to delegates
on catch-up via the conference app until 30 August 2021. There are 36 CPD points allocated to the meeting. Members wishing to register for the recorded portion of the meeting should use the link in the red bar above.
Access Here
All members may access the Medallist lecture, the President's lecture and the AGM
Evening Sessions
29th April, 6th May, 13th May (7pm - 8pm)
Special Interest Group and Poster Sessions: 3 parallel sessions per evening
29 April
- Welcome and Introduction: David Burn, ABN President
- Jazz Pharmaceuticals:(5 minutes) Obstructive sleep apnoea & excessive daytime sleepiness in MS & other neurological conditions: Gavin Giovannoni, Adrian Williams
- SIG 1: MS & Neuroinflammation & posters
- Chair:Tarunya Arun
- Case based discussion in neurosarcoidosis and MS registries and trials project updates
- SARS -CoV2 vaccinations in MS-a moving target: Klaus Schmierer
- UK MS register sub study: COVID-19 and Multiple Sclerosis: Nikos Evangelou
- UK Consortium of MS Trials and registries: Emma Tallantyre
- Posters(4)
- Ten year follow-up surveillance of paediatric Acquired Demyelinating Syndromes (ADS) in the UK: Omar Abdel-Mannan
- Sustained reduction of disability and cognitive decline with long-term siponimod in EXPAND active SPMS patients: Gavin Giovannoni
- Remyelination in people with MS due to an RXR agonist is age-dependent: Chris McMurran
- Disability and quality of life changes in people with MS (pwMS) throughout the COVID-19 pandemic: Rod Middleton
- SIG 2: Functional Disorders
- Chair:Markus Reuber
- Introduction to FCD: diagnosis and concepts: Laura McWhirter
- Epidemiology: Harriet Ball
- Using language to assess memory complaints: Daniel Blackburn
- SIG 3: Headache & posters
- Chair: Mark Weatherall
- What's new in disorders of CSF pressure?
- Idiopathic intracranial hypertension (IIH) Alex Sinclair
- Spontaneous intracranial hypotension (SIH) Manjit Matharu
- Q&A on management of IIH and SIH
- Posters (4)
- Switching CGRP monoclonal antibodies for chronic migraine: real-world outcomes of 37 episodes: Manjit Matharu
- How much weight loss is required to reduce intracranial pressure in idiopathic intracranial hypertension?Susan Mollan
- Efficacy of Fremanezumab in Chronic Migraine Patients With Inadequate Response to ≥3 Preventive Medication Classes: Eoin Sherwin
- Evaluation of 3 Month Data for the Use of Erenumab for Chronic Migraine in Glasgow: Krishna Dani
6 May
- Welcome: Tom Warner, ABN President Elect
- SIG 4: Movement Disorders& posters
- Chair:Mark Edwards
- How should we respond to negative neuroprotection clinical trials in Parkinson’s disease? New models for clinical trials: Camille Caroll & Tom Foltynie
- Live poster presentations chaired by Mark Edwards
- Posters(4)
- Functional genomics and transcriptomics further characterise and potentially improve diagnostic yield of hereditary ataxias: Zhongbo Chen
- Evaluating a Home-Based Care Pathway for People with Parkinson's Disease: Emma King
- Cortical sensorimotor representations remain normal in musicians’ dystonia despite global deficit in dexterity: Anna Sadnicka
- Emerging parkinsonism in the PREDICT-PD cohort after 5-year follow-up: Cristina Simonet
- Two movement disorder video case presentations
- SIG 5: Cognitive Disorders
- Chair: Daniel Blackburn
- Local experience of CSF biomarkers for AD: Akram Hosseini
- FTD or not FTD that is the question: Tobias Langheinrich
- Live poster presentations chaired by Daniel Blackburn
- Posters(4)
- Validation of the Diagnostic Criteria for Sporadic Creutzfeldt-Jakob Disease: Neil Watson
- A review of the performance of referring centres in diagnosing sCJD on MRI: Danielle Sequeira
- Machine learning accurately determines the population prevalence of Alzheimer's disease based on microbiome profile: Amedra Basgaran
- Neuroanatomical signatures of genetic risk for Alzheimer's Disease in healthy adults: Cameron Watson
- SIG 6: Sustainability & posters
- Chair: Sui Wong
- How neurologists can help make life and health services sustainable: Richard Smith (15-20 min talk + discussion)
- Sharing best-practices and initiatives:
- Short Term Feasibility Study in Epilepsy (5 min): Sanjay Sisodiya
- Academia & Sustainability (5 min): Rustam Al-Shahi Salman
- On panel: John Woolmore
- Behind the scenes for Q&A: Jan Coeburgh
- Posters (4)
- Listen to Learn: Podcast-Series for IMT Induction at National Hospital for Neurology and Neurosurgery (NHNN): Sabahat Iqbal
- Reducing the environmental impact of junior doctors at Queen Square: Dominic Wilkins
- The future of outpatient appointments – Do patients with epilepsy prefer remote consultations? Smriti Bose
- Experiences of remote consulting for neurologists and patients during the COVID-19 pandemic – a national survey: Maria Stavrou
13 May
- Welcome: Richard Davenport, ABN Meeting Secretary
- Poster session 1
- Sofia Eriksson, Keith Muir & Huw Morris
- Language Decline Following White Matter Tract Damage During Anterior Temporal Lobe Resection in Language Dominant Hemisphere: Lawrence Binding
- Utilising optical coherence tomography measures as surrogates for raised intracranial pressure in idiopathic intracranial hypertension: Susan Mollan
- Safety, β-sarcoglycan expression and functional outcomes from systemic gene transfer of rAAVrh74.MHCK7.SGCB in LGMD2E/R4: James Richardson
- The National Audit of Seizure Management in Hospitals – Round 3 (NASH 3): Graham Powell
- Investigatory Imaging in Autoimmune-Paraneoplastic Encephalitis: Arshia Seddigh
- Early lowering of blood pressure after acute intracerebral haemorrhage: systematic review and meta-analysis of patient-level data: Tom Moullaali
- Automated Classification of inter-ictal EEG in the diagnosis of epilepsy: Rohan Ahmed
- A retrospective cohort study of cavernous sinus/ orbital apex syndromes presenting to Imperial College London: Aravindhan Baheerathan
- New insight into dysautonomia in GFAP astrocytopathy: Yee Yen Goh
- Limb girdle muscular dystrophy R12 (LGMD 2L, anoctaminopathy) presenting as refractory myositis: a case series: Italo Marago
- Magnetic Resonance Spectroscopy to detect markers of brain injury in Tuberculous Meningitis (TBM): Angharad Davis
- Poster session 2
- Kevin Talbot, Holger Allroggen & Jon Sussman
- Motor network remodelling in ALS and PLS: Evan Edmond
- Secondary syphilis presenting as acute unilateral visual loss in an immunocompetent elderly patient Srinivasa Paluri
- Cerebral Venous Sinus Thrombosis and COVID-19: Causation or Coincidence?: James Crawford
- A pilot study assessing choroidal thickness in frontotemporal dementia and motor neuron disease: Yingdi Chen
- Is it 'CLIPPERS'? Is it CNS Hemophagocytic Lymphohistiocytosis (HLH)?: Amitav Parida
- Pooled safety data from the risdiplam clinical trial development programme: Laurent Servais
- Investigating the molecular mechanisms of mutant C9orf72 human iPSC-derived astrocyte-mediated motor neuron deficits: Maria Stavrou
- Baseline variation in commonly used inflammatory neuropathy clinical outcome measures: Ryan Keh
- Autoimmune Autonomic Neuropathy on the Adie Spectrum – “Ross Syndrome?” Amedra Basgaran
- A qualitative study of patient perceptions of immunoglobulin treatment regimens for inflammatory neuropathy: Emma Callanan
- Adherence to the ABN Guidelines for the Diagnosis and Management of Myasthenia Gravis: Joseph Welch
- The prevalence and management of saliva problems in motor neuron disease: Iona Pearson
- Poster session 3
- Ruth Dobson & Olga Ciccarelli
- A case of natalizumab-related Progressive Multifocal Leukoencephalopathy treated with pembrolizumab: Rebecca Robinson
- Benefit-risk of ofatumumab in treatment-naïve early relapsing multiple sclerosis patients: Dieter Haering
- Treatment escalation in Secondary Progressive MS identified clinically and algorithmically in Relapsing Remitting (RR)MS: Richard Nicholas
- Paramagnetic Rims are a specific biomarker in Multiple Sclerosis: Christopher Allen
- Updated analysis of pregnancy outcomes in a dimethyl fumarate exposure registry: David Rog
- UK Multiple Sclerosis Register: Understanding the Gaps between Patient Outpatient Experiences and Preferences: Rachael Kee
- Virtual Multiple Sclerosis (MS) clinics during a global pandemic: the patients’ perspective: Stephen Ramsay
- Improving care of multiple sclerosis-associated uveitis in a tertiary referral centre in Northern Ireland: John Logan
- The importance of the multidisciplinary team (MDT) in the management of patients with multiple sclerosis: Stephen Ramsay
- A UK multicentre audit on the use of MRI in Multiple Sclerosis: Christopher Allen
- Beyond diagnosis - Patient perception of lumbar puncture for clinical management and/or research studies: Rebecca Robinson
9am
Trainees' session
Programme
- 9:15: Welcome
- 9:30: My Top Mistake:
- David Nicholl, Birmingham
- Rajiv Mohanraj, Manchester
- 10:45 - Parkinson's Disease:
- Psychiatric and cognitive syndromes/presentations in Parkinson’s:
- Acute presentations in PD/Care in late stage Parkinson’s, and managing the non-motor complications:
- Annette Schrag, Royal Free
- 11:45 - Q&A
- 12:05 - Close
12:55pm
Introduction to ABN meeting
David Burn
1pm
Plenary Session 1
Dementia: connecting the dots
Chair: Masud Husain
- Biomarkers for dementia – There Will Be Blood:
- Advanced therapies for dementia: new revolution or false dawn?:
2pm
- Dementia & Epilepsy
- Chair: Chris Kipps
- 1, Speech-in-noise perception is a marker of preclinical Alzheimer’s disease, Cameron Watson
- 2, Population-based blood screening for pre-clinical Alzheimer’s disease: a British birth cohort at age 70 Ashvini Keshavan
- 3, Deep phenotyping of frontal lobe epilepsy compared to other epilepsy syndromes Ryan Wee
- 4, Pre-pregnancy and antenatal care of women with epilepsy Taief Miah
- Multiple Sclerosis
- Chair:Neil Robertson
- 1, Retinoid-X receptor agonism promotes remyelination in relapsing-remitting multiple sclerosis: a phase 2 clinical trial William Brown
- 2, UK Multiple Sclerosis service audit of 70 centres [4] Access to neuroradiology. Jeremy Hobart
- 3, COVID-19 and multiple sclerosis: An updated report of the community-based longitudinal UK MS Register study. Afagh Garjani
- 4, CSF-resident CD4+ T-cells display a distinct gene expression profile relevant to multiple sclerosis. James Hrastelj
- Movement Disorders
- Chair: Mark Edwards
- 1, Biomarkers for brain injury and copper toxicity in Wilson's disease: A diffusion tensor imaging study. Samuel Shribman
- 2, Improving the early diagnosis of corticobasal syndrome: a large clinico-pathological study Danielle Lux
- 3, Lower lymphocyte count is associated with increased risk of Parkinson’s disease. Melanie Jensen
- 4, Visual dysfunction predicts cognitive impairment and white matter degeneration in Parkinson’s disease. . Angeliki Zarkali
Pharma Interlude (2:45pm)
- GW Pharmaceuticals: Lennox-Gastaut syndrome: challenges in diagnosis and transition
- Novartis: High Efficacy Treatment (HET) for MS in a changing world
- Kyowa Kirin: Management of Parkinson's disease: an update for clinicians
- Muscle and Nerve
- Chair: Charlotte Dougan
- 1, Andersen-Tawil Syndrome: Multi-System Deep Phenotyping of a large UK cohort. Vinojini Vivekanandam
- 2, SUNFISH Part 2: 24-month efficacy and safety of risdiplam in Type 2/3 SMA. Giovanni Baranello
- 3, Charcot-Marie-Tooth Disease secondary to biallelic mutations in SORD. Chris Record
- 4, Good outcomes after aggressive treatment of immune checkpoint inhibitor related myasthenia gravis: a case series. Jamie Weaver
- Inflammatory and Neurogenetics
- Chair: Fiona Norwood
- 1, Neurologic and radiographic findings associated with Paediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 (PIMS-TS). Omar Abdel-Mannan
- 2, Genomic features specific to the human lineage are associated with neurological diseases and intelligence. Zhongbo Chen
- 3, White matter Hyperintensities and Brain Microbleeds in Ataxia-Telangiectasia: the Cambridge cohort. May Yung Tiet
- 4, L-arginine and mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS): a systematic review. Yi Shiau Ng
- Neuro-Ophthalmology and TBI
- Chair: Arani Nitkunan
- 1, Bariatric surgery versus community weight management intervention for idiopathic intracranial hypertension: A randomised controlled trial. Susan Mollan
- 2, A randomised controlled, trial of the GLP-1 receptor agonist Exenatide in Idiopathic Intracranial Hypertension. James Mitchell
- 3, Advanced blood and neuroimaging biomarkers of axonal injury after TBI in the prospective multi-centre BIO-AX-TBI study. Neil Graham
- 4, Detailed evaluation of cognitive performance in Idiopathic Intracranial Hypertension and relevance of intracranial pressure. Olivia Grech
Pharma Interlude (3:45pm)
- Novartis Gene Therapies: Gene replacement therapy for spinal muscular atrophy (SMA) in clinical practice
- Janssen: The many sides of MS
- Arvelle: Is seizure freedom an impossible goal?
4:45pm
Case Competition
Chair: Lucy Kinton
- 1, When the rhythm moves you, Anisha Doshi
- 2, Yuletide tremor, twitches and tunes, Maryam Talaei
- 3, A case of encephalopathy following a 10k run, Claire Carstairs
- 4, Nuclear countdown, Daniel Rice-Wilson
- 5, A man with Erb’s disease, Sara Leddy
- 6, A localisation issue, Laura Midgley
9am
Plenary Session 2
Connecting neurologists and complex therapies
Chair: Carolyn Gabriel
- The neurological application of Bone marrow and Stem cell therapies:Charalampia Kyriakou, UCL
- Why/how/when don't we use B cell depleting therapies earlier in neurology?:Katy Murray, Edinburgh
10am
ABN Medallist
Neuroinflammation: moving on
Neil Scolding, Bristol
Citation: Roger Barker
10:45am
Pharma Interlude
- Teva: Monoclonals for Migraine: Our Experience.
- Alex Sinclair, Mark Weatherall, Jane Anderson & Shazia Afridi
- Biogen: SMA in Adults: A UK perspective.
11:15am
Plenary Session 3: Intimate connections
Chair: Matt Jones
- Return of the spirochaete:Margaret Kingston, Manchester
- Dopaminergic therapies and PD: time for a new direction?:Oliver Rascol, Toulouse
12:15pm
President's Lecture:
Circuits and Connections
Tom Warner
1pm
Clinicopathological conference and close
Chair: Richard Davenport
Discussant: Paul Reading
The Great Reveal: Marija Cauchi
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